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Article

Predicting response to immunochemotherapy in EGFR-mutant lung adenocarcinoma after third-generation TKI resistance using CT radiomics-based habitat imaging.

Frontiers in immunology - 1 Jan 2026

Qie Shuai, Shi Yasong, Li Jingyun, Jia Sicong, Yin Xiaoping

Abstract excerpt

Background: Third-generation epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI) resistance poses a significant therapeutic challenge in advanced lung adenocarcinoma. This study aimed to develop and validate a computed tomography (CT)-based habitat radiomics model for predicting response to immunochemotherapy in EGFR-mutant lung adenocarcinoma patients after TKI resistance. Methods: This...

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Share to Adenocarcinoma of Lung
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42311663
DOI: 10.3389/fimmu.2026.1785968
PMCID: PMC13269283

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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