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Understanding shared and sex-specific considerations in hereditary breast and ovarian cancer (HBOC) testing decision-making in Singapore.

Journal of genetic counseling - 1 Jun 2026

Yuen Jeanette, Chua Ziyang, Lim Khai Shin Alva, Rahadian Rayhan Erlangga, Ishak Nur Diana Binte, Li Shao-Tzu, Zhang Zewen, Chiang Jianbang, Ngeow Joanne

Abstract excerpt

Hereditary breast and ovarian cancer (HBOC) genetic testing identifies pathogenic variant carriers to guide cancer risk management. Although prior research suggests that healthcare decisions-including risk assessment, screening, and treatment-may differ between males and females, the influence of assigned sex at birth on HBOC testing decisions remains underexplored. Twenty-eight participants (10 males, 18...

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Identifiers

PMID: 42295046
DOI: 10.1002/jgc4.70247

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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