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Article

Evolutionary dynamics and molecular adaptation of Rift Valley fever virus across human and non-human outbreaks in Africa.

BMC genomics - 15 Jun 2026

Omara Isaac Emmanuel, Juma John, Tshiabuila Derek, Dor Graeme, Wilkinson Eduan, Baxter Cheryl, Tegally Houriiyah, Moir Monika, Oyola Samuel O, de Oliveira Tulio

Abstract excerpt

BACKGROUND: Rift Valley fever virus (RVFV) is an emerging zoonotic virus of major public health and veterinary concern across Africa. Although past genomic studies have focused on outbreak response and lineage classification, the molecular mechanisms driving viral persistence and adaptation remain poorly understood. This study aimed to identify RVFV protein-coding mutations and adaptive signatures across multiple...

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Identifiers

PMID: 42289653
DOI: 10.1186/s12864-026-13002-4
PMCID: PMC13495268

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