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Integrative Multi-Omics Analysis Identifies Novel Enhancer Variants on SSC2 Associated With Backfat Thickness in Landrace Pigs.

Animal genetics - 1 Jun 2026

Feng Xigang, Zhou Xiuqi, Liang Hao, Li Jingjin, Yu Mei, Zhao Shuhong, Li Xinyun, Li Xiaoping

Abstract excerpt

Backfat thickness is an economically important trait in pig production, yet the functional regulatory variants underlying it remain poorly characterized. Here, we performed a genome-wide association study (GWAS) for backfat thickness at 100 kg (BF100) in a large Landrace population (n = 5923) using 13.46 million imputed SNPs. We identified two significant quantitative trait loci (QTLs) on SSC2 (1.21-3.69 Mb;...

Topics

Animals
Quantitative Trait Loci
Polymorphism, Single Nucleotide
Sus scrofa
Genome-Wide Association Study
Multiomics
Enhancer Elements, Genetic
Phenotype
Adipose Tissue
Promoter Regions, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Female

Source

Identifiers

PMID: 42264465
DOI: 10.1002/age.70141

Genes

ASGR1
CTSD
GPS2
IGF2
TP53
TSPAN32
TSSC4
YBX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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