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Co-Circulation and Mixed Infections of Classic and Melbourne Human Astroviruses Among Pediatric Acute Gastroenteritis Patients in Japan, 2018-2024.

Journal of medical virology - 1 Jun 2026

Ushijima Hiroshi, Onda-Shimizu Yuko, Kotaki Tomohiro, Nishimura Shuichi, Kobayashi Masaaki, Okitsu Shoko, Hussain Mudassar, Müller Werner E G, Kobayashi Takeshi, Komine-Aizawa Shihoko, Maneekarn Niwat, Khamrin Pattara

Abstract excerpt

Simultaneous infection with multiple viral genotypes can occur, especially during outbreaks. This study examined mixed infections of classic human astrovirus (HAstV) and Melbourne (MLB) HAstV in Japan over 6 years (July 2018-June 2024), spanning the pre- and post-COVID-19 periods. Two molecular approaches were used: (1) conventional RT-PCR with clade-common primers targeting the RNA-dependent RNA polymerase...

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PMID: 42253237
DOI: 10.1002/jmv.71002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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