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Article

Variations in DNA Methylation Are Landmarks of Freshwater Adaptation in Three-Spined Sticklebacks.

International journal of molecular sciences - 11 May 2026

Starshin Alexey, Mazur Alexandr, Mugue Nikolai, Kaplun Daria, Golden Artemiy, Khrameeva Ekaterina, Prokhortchouk Egor

Abstract excerpt

Understanding the phenotypic consequences of epigenetic variation and its role in adaptation remains a central challenge in evolutionary biology. Marine and freshwater sticklebacks provide a powerful system to study the interplay between genetic and epigenetic components of phenotypic plasticity that enables colonization of contrasting salinity habitats. Here, we used whole-genome bisulfite sequencing (WGBS) to...

Topics

Animals
DNA Methylation
Smegmamorpha
Fresh Water
Epigenesis, Genetic
Adaptation, Physiological
Genetic Variation
Salinity

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 42196248
DOI: 10.3390/ijms27104265
PMCID: PMC13207980

Genes

ARID5B
BPTF
TET1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-42196248-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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