Article
Network topology of the gut microbiome associates with metabolic health in obesity.
Nature communications - 13 May 2026
Lacruz-Pleguezuelos Blanca, Pérez-Cuervo Alba, Coleto-Checa Diego, Bazán Guadalupe X, Romero-Tapiador Sergio, Freixer Gala, Fernández-Cabezas Jorge, Aguilar-Aguilar Elena, Martín-Segura Adrián, Cárdenas-Roig Nicolás, Carrasco-Guijarro Lucía, Fernández Lara P, Espinosa-Salinas Isabel, Ramírez de Molina Ana, Morales Aythami, Tolosana Ruben, Ortega-Garcia Javier, Pancaldi Vera, Marcos-Zambrano Laura Judith, Carrillo de Santa Pau Enrique
Abstract excerpt
Obesity is a heterogeneous condition comprising a continuum of phenotypes with various metabolic and inflammatory profiles. Metabolically healthy obesity (MHO) identifies individuals with obesity but a relatively preserved metabolic state, although little is known about the gut microbiome features underlying this phenotype. Here, we analyzed gut microbial network structures of 931 individuals living with...
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