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Article

Pyrethroids resistance and distribution of kdr mutations (L1014F and N1575Y) in Anopheles gambiae s.l. along the south-north transect of Benin.

Malaria journal - 10 May 2026

Ossé Razaki A, Hougbe Steve Zinsou, Ahouandjinou Minassou Juvenal, Sidick Aboubacar, Affolabi Zul-Kifl, Koumodji Koffi Djigbodi, Tokponnon Filémon, Aikpon Rock, Sovi Arthur, Orou Haziz A Sina, Baba-Moussa Lamine, Akogbeto Martin

Abstract excerpt

BACKGROUND: Pyrethroid resistance in Anopheles gambiae s.l. compromises malaria vector control in sub-Saharan Africa. In Benin, resistance has been documented for over two decades, but the geographic distribution of emerging mutations such as N1575Y remains poorly characterized. This study investigated pyrethroid susceptibility, kdr mutations, and metabolic resistance mechanisms across twelve communes spanning a...

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Identifiers

PMID: 42108440
DOI: 10.1186/s12936-026-05932-x
PMCID: PMC13330041

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