Recurrent primary hyperparathyroidism with ipsilateral multifocal papillary thyroid carcinoma of classical, warthin-like, and follicular variants harboring distinct BRAF and NRAS mutations: a rare case report.

Abstract excerpt

BACKGROUND: The coexistence of primary hyperparathyroidism (PHPT) and papillary thyroid carcinoma (PTC) occurs in 2-5% of surgical series. Recurrent PHPT following parathyroidectomy presents additional clinical challenges. While synchronous PHPT and PTC have been documented, the simultaneous occurrence of multifocal PTC exhibiting three distinct histological variants with different oncogenic driver mutations,...

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