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Article

Vacuolar iron transporters mediate resistance to triadimefon in plant pathogenic fungi.

Nature communications - 6 May 2026

Ji Fan, Du Youwei, Liu Yaning, Liu Bofan, Gao Xinpei, Feng Yaoxuan, Liu Xinyun, Huang Lili, Guo Jun, Kang Zhensheng, Zhan Gangming

Abstract excerpt

Triadimefon resistance in Puccinia striiformis f. sp. tritici (Pst), the fungal pathogen of wheat stripe rust, is increasingly observed in China, but the mechanisms beyond cytochrome P450 14α-demethylase (Cyp51) mutations remain unknown. Through bulked segregant analysis and RNA-seq of a sexual Pst population, we identify three vacuolar iron transporter genes (CCC1), PstCCC1.1, PstCCC1.2 and PstCCC1.3, as key...

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Identifiers

PMID: 42091877
DOI: 10.1038/s41467-026-72157-6
PMCID: PMC13376413

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