Article
Transplant of serologic A1 but genotype A2 kidneys to ABO O and B recipients is feasible and safe.
Human immunology - 1 Jul 2026
Thalji Nassir M, Kapturczak Matthias, Shaker Tamer, Chand Ranjeeta, Lane William J, Murphey Cathi
Abstract excerpt
BACKGROUND: Kidney transplants from ABO A2 donors to O and B recipients reduce wait times without compromising outcomes. Recent work shows that ABO genotyping more accurately identifies A2 donors than serologic methods. Here, we show that kidneys from donors labeled A1 by serology but genotyped as A2 can be safely transplanted to O and B recipients with favorable outcomes, expanding access for disadvantaged...
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