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Age-Associated Targetable Genomic Alterations and PD-L1 Expression in 2509 Patients With Pulmonary Ground-Glass Opacities.

Cancer medicine - 1 May 2026

Tang Wen-Fang, Huang Si-Qi, Lin Yi-Duo, Li Hong-Ji, Huang Qing-Hua, Chen Jing, Qiu Zhen-Bin, Huang Wei-Zhao, Wu Ying-Meng, Ye Hong-Yu, Xu Wei, Yang Xue-Ning, Wu Yi-Long, Jiang Hai-Ming, Liang Yi, Tang Xuan, Zhong Wen-Zhao

Abstract excerpt

AIM: To investigate the landscape of targetable genomic alterations and programmed cell death ligand 1 (PD-L1) expression in pulmonary ground-glass opacities (GGOs) and their association with age. METHODS: A total of 2509 patients with GGOs were retrospectively analyzed. Tumor characteristics, PD-L1 expression, and prevalence of targetable alterations were compared across age groups. RESULTS: In GGOs, the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42068110
DOI: 10.1002/cam4.71811
PMCID: PMC13135135

Genes

ALK
EGFR
ERBB2
KRAS
MET
RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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