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Article

RNA Virus Diversity, Cross-Species Transmission, and Molecular Constraints in Two Closely Related Rat Species.

Integrative zoology - 1 Sept 2026

Li Zhiming, Zhang Mingyu, Cao Ruidong, Shi Chengmin, Yang Le, Zhang Jianxu, Zhang Yaohua

Abstract excerpt

Viral infection involves co-evolution with hosts, yet the molecular determinants that constrain viral cross-species transmission remain poorly understood. Here, we established conspecific and heterospecific co-housing models for two closely related rat species, Rattus norvegicus (RN) and Rattus tanezumi (RT), both maintained in laboratory settings for over 10 generations, together with wild-caught RT individuals....

Read the complete abstract on PubMed

Topics

Animals
Rats
RNA Viruses
Species Specificity
Rodent Diseases
Genetic Variation
RNA Virus Infections

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Identifiers

PMID: 42033733
DOI: 10.1111/1749-4877.70104
PMCID: PMC13574172

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