Early maternal DHA supplementation fails to modify clinical phenotypes associated with impaired placentation: A randomized, double-blind, placebo-controlled trial (DEEPER trial).

Abstract excerpt

BACKGROUND: Defective deep placentation contributes to major obstetric complications, including preterm birth, preeclampsia (PE), and severe fetal growth restriction (FGR). Docosahexaenoic acid (DHA) supplementation may improve placental function, but evidence from randomized trials remains inconsistent. OBJECTIVE: To evaluate whether early DHA supplementation modifies clinical phenotypes associated with impaired...

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