Article
Chromosomal fusions trigger rediploidization of autopolyploid genomes.
Nature - 1 Jun 2026
Xie Chuanshuai, Ma Zitu, Zhou Chaowei, Ma Kexin, Wang Haoyu, Wu Jiahong, Zhou Yan, Lu Yongrui, Ji Da, Gu Xuedie, Gao He, Li Junting, Fu Suxing, Li Weiqiang, Han Zhaofang, Xiao Shijun, Liu Fei, Zeng Benhe, Chen Sheng'ao, Niu Jiangong, Zhang Tao, Shen Jian, Liu Chunna, Luo Jing, Macqueen Daniel J, Meyer Axel, Liu Haiping, Xu Luohao
Abstract excerpt
The ancestor of all vertebrates is thought to have undergone autopolyploid whole-genome duplication (WGD)1,2, doubling the genetic raw material for evolutionary diversification3-5. However, we still do not understand the first steps of rediploidization that followed, required for the emergence and divergence of duplicated genes (ohnologues) created by WGD6,7. Consequently, how the functional potential created by...
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