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Dynamic Fusion of Genomics and Functional Network Connectivity in UK Biobank Reveals Schizophrenia-Related SNP Manifolds.

Human brain mapping - 15 Apr 2026

Chen Jiayu, Iraji Armin, Fu Zening, Duda Marlena, Andrés-Camazón Pablo, Thapaliya Bishal, Liu Jingyu, Calhoun Vince D

Abstract excerpt

Many mental disorders show strong genetic influence. In parallel, dynamic functional network connectivity (dFNC) has shown high sensitivity to brain changes related to mental disorders. However, previous studies linking dFNC to genetics largely follow a paradigm to identify associations between one set of genetic factors and multiple sets of connectivity features from different dFNC states, ignoring the potential...

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PMID: 42010738
DOI: 10.1002/hbm.70530
PMCID: PMC13095861

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