The CD4/CD8 ratio as an immune phenotype improves risk stratification for sepsis-associated acute kidney injury: A single-center, multi-ICU Chinese cohort study.

Abstract excerpt

BACKGROUND: Sepsis-associated acute kidney injury (SA-AKI) is a common and severe complication in critically ill patients, yet current risk stratification lacks immune-specific biomarkers. The CD4/CD8 T cell ratio, a key indicator of immune homeostasis, has shown prognostic value in sepsis, but its specific association with, and incremental value for predicting, SA-AKI risk in Chinese ICU populations remains...

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• Acute Kidney Injury
• CD4-CD8 Ratio
• Critical Illness
• East Asian People
• Flow Cytometry