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Article

Native liver survival and genetic associations in Korean patients with Alagille syndrome.

European journal of pediatrics - 10 Apr 2026

Choi Shinjie, Kim Dong-Uk, Kim Yeji, Kim Lia, Shim Jung Ok, Moon Jin Soo, Hahn Jong Woo, Yang Hye Ran, Chang Ju Young, Ko Jae Sung

Abstract excerpt

Alagille syndrome (ALGS) is a rare multisystem disorder most commonly resulting from pathogenic variants in JAG1 and, less frequently, NOTCH2. We evaluated long-term native liver survival (NLS) and overall survival (OS) in a Korean ALGS cohort and compared the genetic characteristics of this cohort with those of the Global ALagille Alliance (GALA) study cohort. We retrospectively reviewed 60 patients with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41961327
DOI: 10.1007/s00431-026-06917-3
PMCID: PMC13068675

Genes

JAG1
NOTCH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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