Dynamics of leukocyte populations, immune-regulatory cytokines, and biochemical parameters in wild boar and domestic pigs experimentally infected with a virulent African swine fever virus genotype II strain.

doi:10.3389/fimmu.2026.1751646

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Dynamics of leukocyte populations, immune-regulatory cytokines, and biochemical parameters in wild boar and domestic pigs experimentally infected with a virulent African swine fever virus genotype II strain.

Frontiers in immunology - 1 Jan 2026

Franzoni Giulia, Lean Fabian Zhi Xiang, Giaconi Emanuela, Tedde Giuseppe, Zinellu Susanna, Nicolussi Paola, Le Dimna Mireille, Le Potier Marie-Frédérique, Steedman Elliot, Crooke Helen Rachel, Righi Cecilia, Petrini Stefano, Rayón Noemí, Gavier-Widen Dolores, Núñez Alejandro, Sanchez-Cordon Pedro Jose

Abstract excerpt

African Swine Fever Virus (ASFV) is the causative agent of devastating disease affecting domestic and wild pigs globally. A previous study of the intranasal inoculation of domestic pigs (DP) and wild boar (WB) with the ASFV genotype II strain "Armenia 2007" demonstrated distinct disease outcomes. This study aims to compare the leukocyte, cytokine and biochemical profiles in experimentally infected DP and WB....

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PMID: 41953012
DOI: 10.3389/fimmu.2026.1751646
PMCID: PMC13054600

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