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Article

Mapping the neuropathic-sensory-affective pain axis in Sjögren's disease toward neuropsychological phenotyping.

Journal of autoimmunity - 1 May 2026

Gandolfo Saviana, Riccio Flavia, Irace Rosaria, Mauro Daniele, Ciancio Antonio, Forte Giulio, Ciccia Antonio Mario, Tirri Enrico, Ciccia Francesco

Abstract excerpt

BACKGROUND: Pain is one of the most disabling manifestations of Sjögren's disease (SjD). Whether neuropathic descriptors, sensory abnormalities and depressive symptoms represent distinct or integrated dimensions of the SjD phenotype is unknown. OBJECTIVES: To characterize the prevalence, correlates and clinical relevance of neuropathic pain symptoms and bedside sensory abnormalities in SjD, and to explore how...

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Identifiers

PMID: 41950774
DOI: 10.1016/j.jaut.2026.103551

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