Spatio-temporal dynamics of Hendra virus in Australia reveal stable maintenance of diverse viral clades among Pteropus bats.

doi:10.1038/s41564-025-02254-7

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Spatio-temporal dynamics of Hendra virus in Australia reveal stable maintenance of diverse viral clades among Pteropus bats.

Nature microbiology - 1 Apr 2026

Yinda Claude Kwe, Eden John-Sebastian, Prates Erica T, Vlot Anna, van Tol Sarah, Anzick Sarah L, Wang Jianning, Halpin Kim, Borremans Benny, Lunn Tamika J, Barbian Kent, Bulloch Brown, Greene Benjamin, Meade-White Kimberly, Bushmaker Trenton, Falvo Caylee A, Crowley Daniel E, Jones-Slobodian Devin N, Shah Manesh, Pavicic Mirko, Carr William, Martens Craig, Jacobson Daniel, Plowright Raina K, Peel Alison J, Munster Vincent J

Abstract excerpt

Hendra virus (HeV) was discovered in 1994 in Australia. Limited genomic data have hindered comprehensive understanding of HeV's evolutionary dynamics. Here we recovered 48 HeV genomes from bats and 9 from horses from Australia between 2016 and 2020, revealing four distinct clades. Each clade was distributed over a large spatial area with multiple clades co-circulating within a single bat roost on the same day and...

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PMID: 41946873
DOI: 10.1038/s41564-025-02254-7
PMCID: PMC13056563

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