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Article

Post-ACTH peak cortisol response is associated with genotype in children with nonclassic congenital adrenal hyperplasia.

Frontiers in endocrinology - 1 Jan 2026

Dayno Allie N, Kilberg Marissa J, Gonter Erin, Gallop Robert, Squicciarini Jacob, Montano Carolina, Vogiatzi Maria G

Abstract excerpt

Introduction: Suboptimal cortisol levels after ACTH stimulation have been recently reported in approximately 30% of patients with nonclassic congenital adrenal hyperplasia (NCCAH). There is little information on the role of genotype on cortisol secretion in NCCAH. The aim of this study is to investigate the association between genotype (i.e compound heterozygote for one mild and one severe CYP21A2 variant vs....

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Share to Adolescent
Share to Adrenal Hyperplasia, Congenital

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Child, Preschool

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Share to Steroid 21-Hydroxylase

Source

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Identifiers

PMID: 41938119
DOI: 10.3389/fendo.2026.1745992
PMCID: PMC13046529

Genes

CYP21A2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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