Complex Patterns of Hitchhiking Mutation Load Among Stickleback Populations.

Abstract excerpt

Positive selection causes beneficial alleles to rise to high frequency in a population. This can cause linked genetic variation to "hitchhike," and thereby also rise in frequency. This linked variation may include deleterious recessive alleles, previously neutrally harbored at low frequency and in heterozygous genotypes. Modeling studies have shown that local effective population size and reduced recombination...

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