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The transcription factor WRKY13 activates BRUTUS to maintain iron homeostasis in Arabidopsis.

Plant & cell physiology - 28 Jul 2026

Song Hui, Chen Yifan, Chen Guangna, Li Shuangyao, Xu Shuxun, Zhang Jing, Wu Xi, Cao Shuqing

Abstract excerpt

Iron (Fe) is a fundamental micronutrient for plant and animal physiology. Consequently, Fe limitation in agricultural systems not only compromises crop productivity but also poses a significant threat to human nutritional security. Due to the limited bioavailability of Fe in the soil, plants have evolved adaptive strategies that can regulate Fe absorption and internal balance, thereby optimizing their survival...

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PMID: 41914641
DOI: 10.1093/pcp/pcag041

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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The transcription factor WRKY13 activates BRUTUS to maintain iron homeostasis in Arabidopsis.PMID 41914641Read ↗

BRUTUS and its paralogs, BTS LIKE1 and BTS LIKE2, encode important negative regulators of the iron deficiency response in Arabidopsis thaliana.Semantic proximity Read ↗

The BRUTUS-LIKE E3 ligases BTSL1 and BTSL2 fine-tune transcriptional responses to balance Fe and Zn homeostasisSemantic proximity Read ↗

A WRKY Transcription Factor Regulates Fe Translocation under Fe Deficiency.Semantic proximity Read ↗

The bHLH transcription factor bHLH104 interacts with IAA-LEUCINE RESISTANT3 and modulates iron homeostasis in Arabidopsis.Semantic proximity Read ↗

Elongated Hypocotyl 5 (HY5) regulates <i>BRUTUS</i> ( <i>BTS</i> ) to maintain Iron homeostasis in <i>Arabidopsis thaliana</i>Semantic proximity Read ↗

FIT and bHLH Ib transcription factors modulate iron and copper crosstalk in Arabidopsis.Semantic proximity Read ↗

Iron excess in rice: from phenotypic changes to functional genomics of WRKY transcription factors.Semantic proximity Read ↗

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Arabidopsis bHLH100 and bHLH101 control iron homeostasis via a FIT-independent pathway.Semantic proximity Read ↗

Interaction between the bHLH transcription factor FIT and ETHYLENE INSENSITIVE3/ETHYLENE INSENSITIVE3-LIKE1 reveals molecular linkage between the regulation of iron acquisition and ethylene signaling in Arabidopsis.Semantic proximity Read ↗

bHLH11 inhibits bHLH IVc proteins by recruiting the TOPLESS/TOPLESS-RELATED corepressors.Semantic proximity Read ↗

Transcriptome analysis of iron over-accumulating Arabidopsis genotypes uncover putative novel regulators of systemic and retrograde signaling.Semantic proximity Read ↗

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