Molecular epidemiological characterization of invasive extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates from infants less than 3 months old in East Asia.

Abstract excerpt

OBJECTIVES: Neonatal sepsis due to Gram-negative bacteria remains a clinical challenge. This study aimed to characterize the current epidemiology, genetic diversity, and antimicrobial resistance of invasive Escherichia coli and Klebsiella pneumoniae infections in infants under 90 days old in Taiwan and Korea. METHODS: Culture-confirmed clinical isolates collected from 2020 to 2023 (Taiwan) and 2015-2023 (Korea)...

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