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The Inheritance Puzzle: A Case of Dual Genetic Kidney Disease.

Nephrology (Carlton, Vic.) - 1 Mar 2026

Shanmugam Sabarinath, Manoharan Karthikeyan, Parameswaran Sreejith, Ganesh Rajesh Nachiappa, Nair Sandhya, Sharma Alok

Abstract excerpt

Autosomal Dominant Polycystic Kidney Disease (ADPKD) and X-Linked Alport Syndrome (AS) are the most common monogenic causes of chronic kidney disease (CKD), each capable of independently leading to end-stage kidney disease (ESKD). However, the concurrent presence of both disorders in a single individual is exceedingly rare and poses significant diagnostic complexity. We report a unique case involving dual...

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Source

Identifiers

PMID: 41765374
DOI: 10.1111/nep.70178

Genes

COL4A5
PKD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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