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Article

Integrated Prenatal Genetic Evaluation of Renal Agenesis: Chromosomal Microarray Analysis, Whole Exome Sequencing, and Outcome Correlations in 203 Fetuses.

Genes - 31 Jan 2026

Zhang Na, Huang Ruibin, Fu Fang, Zhou Hang, Li Ru, Liao Can

Abstract excerpt

OBJECTIVES: To characterize the prenatal phenotypic spectrum, genetic findings, and pregnancy outcomes of fetal renal agenesis (RA), and to clarify the complementary roles of chromosomal microarray analysis (CMA) and whole exome sequencing (WES) in phenotype-stratified prenatal evaluation. METHODS: This retrospective study included 203 RA fetuses between March 2017 and November 2025. All cases underwent...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41751559
DOI: 10.3390/genes17020176
PMCID: PMC12940442

Genes

FRAS1
FREM2
GFRA1
GREB1L

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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