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Article

Clinical Characteristics and Management of Two Cases of Complete Androgen Insensitivity Syndrome With Germ Cell Tumors.

Cancer reports (Hoboken, N.J.) - 1 Feb 2026

Wang Fangming, Wang Dong, Li Jianxing, Xing Nianzeng

Abstract excerpt

BACKGROUND: Androgen insensitivity syndrome (AIS) is an X-linked recessive genetic disorder caused by mutations in the androgen receptor (AR) gene, leading to androgen resistance and disorders of sex development (DSD) in 46, XY individuals. It is classified into three phenotypes: complete (CAIS), partial (PAIS), and mild (MAIS). CAIS is characterized by normal external female genitalia, primary amenorrhea, and a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neoplasms, Germ Cell and Embryonal

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Source

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Identifiers

PMID: 41725111
DOI: 10.1002/cnr2.70491
PMCID: PMC12927923

Genes

AR
AFP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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