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Article

Bilateral juvenile-onset cataracts associated with GCNT2 variants.

Ophthalmic genetics - 1 Aug 2026

Kamel Kerollos M, Scanga Hannah L, Nischal Ken K

Abstract excerpt

PURPOSE: We report a case of juvenile-onset cataracts due to variants in GCNT2, including a novel change within the GCNT2B isoform expressed exclusively in lens epithelial cells. METHODS: A retrospective chart review was conducted. The proband underwent serial ophthalmic examinations and next-generation sequencing (NGS) of 66 genes related to early-onset cataracts. RESULTS: An 8-year-old female (proband) was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41713900
DOI: 10.1080/13816810.2026.2634740

Genes

GCNT2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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