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Article

HPV testing with 16/18 genotyping for risk stratification among women with normal cytology: a multicenter prospective cohort study from China.

Journal of clinical microbiology - 11 Mar 2026

Zhang Jiangong, Wang Hong, Liu Yin, Li Zhifang, Feng Xiangxian, Luo Xiping, Chen Wen, Zhang Shaokai, Yang Hui, Qiao Youlin

Abstract excerpt

To evaluate the clinical performance of Hybribio's 14-type HPV real-time PCR with 16/18 genotyping (HBRT-H14) and its risk stratification utility among women with normal cytology (NILM). From 2017 to 2020, a multicenter cohort enrolled 8,401 women aged 30-64 years with NILM cytology. Baseline HPV testing used HBRT-H14. Women positive for HPV 16/18 were referred for colposcopy; follow-up was annual for 3 years or...

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Identifiers

PMID: 41711488
DOI: 10.1128/jcm.01289-25
PMCID: PMC12977570

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