Article
Functional FTSH4 complexes in Arabidopsis mitochondria: a megacomplex with SLP1 and SLP1-free smaller complexes.
Plant & cell physiology - 30 Jun 2026
Maziak Agata, Heidorn-Czarna Małgorzata, Gehl-Väisänen Bernadette, Kaźmierczak Urszula, Jańska Hanna
Abstract excerpt
The FTSH4 protease is a major component of the Arabidopsis mitochondrial protein quality control system. It has both a proteolytic and a chaperone-like activity and forms complexes anchored in the inner mitochondrial membrane. Here, we show that FTSH4 assembles into two distinct forms: a dominant high-molecular-weight megacomplex with stomatin-like protein 1 (SLP1) and smaller SLP1-free assemblies. In the slp1-1...
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