Article
Mixed primary progressive aphasia and alcohol use disorder: a case of detailed clinical phenotyping outperforming molecular imaging.
Neurocase - 1 Feb 2026
Okoye Obiora, Aguzzoli Cristiano Schaffer, Battista Petronilla, Ramos Claudia, Meenan Karen, Abu Raya Maison, Ratnasiri Buddhika, Rojas Julio C, de Leon Jessica, Miller Bruce, Gorno-Tempini Maria Luisa, La Joie Renaud, Spina Salvatore
Abstract excerpt
Primary progressive aphasia (PPA) refers to a group of clinically and pathologically heterogeneous syndromes characterized by progressive and relatively selective impairment in speech and language as the main cognitive domain in the early disease stage. The main clinical variants of PPA based on current diagnostic criteria include logopenic variant PPA (lvPPA), nonfluent variant PPA (nfvPPA), and semantic variant...
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