Article
Increased mutation rates and diversity are dominant features of Geobacter multiheme cytochromes.
mBio - 11 Mar 2026
Starwalt-Lee Ruth, Gralnick Jeffrey A, Bond Daniel R
Abstract excerpt
Multiheme cytochromes (MHCs) are the central catalysts of extracellular electron transfer and are uniquely abundant in the genomes of model Fe(III)-reducing organisms like Geobacter sulfurreducens. While specific functions for some multiheme cytochromes are known, the complex repertoire present in any genome makes annotation and prediction of electron transfer circuitry challenging. Here, we reveal patterns of...
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