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Article

The pivotal role of etiology in managing Non-CAH primary adrenal insufficiency in pediatric and adolescent populations: A Single-Center study.

Endocrine - 16 Feb 2026

Arslan Emrullah, Solmaz Aslı Ece, Kızılay Deniz Özalp, Akın Haluk, Balkı Hanife Gül, Jalilova Arzu, Gökşen Ruhsar Damla, Darcan Şükran, Özen Samim

Abstract excerpt

BACKGROUND: Primary adrenal insufficiency (PAI) in children, outside of congenital adrenal hyperplasia (CAH), represents a rare and genetically diverse group of disorders often leading to diagnostic delays. Advances in molecular genetics have uncovered a wide spectrum of non-CAH etiologies, yet real-world data from pediatric cohorts remain limited. METHODS: We retrospectively reviewed 11 children diagnosed with...

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PMID: 41697505
DOI: 10.1007/s12020-026-04557-z

Genes

MC2R
ABCD1
NR0B1
AIRE
MRAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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