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[Impact of bone metastasis on the prognosis of lung adenocarcinoma patients treated with third-generation EGFR-TKI and the underlying mechanisms].

Zhonghua yi xue za zhi - 16 Jun 2026

Zhang C, Shi X L, Jiang Y Q, Li J, Xu J L, Guo R H

Abstract excerpt

Objective: To evaluate the impact of bone metastasis on the prognosis of lung adenocarcinoma patients receiving first-line third-generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) and to explore the potential mechanisms by which bone metastasis contributes to EGFR-TKI resistance. Methods: A retrospective analysis was conducted on the clinical data of 370 EGFR-mutant advanced lung...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41672890
DOI: 10.3760/cma.j.cn112137-20251110-02936

Genes

EGFR
CD55
PELI1
CXCL17
PTGS2
SLC7A5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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