Genetic defects in the CDP-choline pathway for phosphatidylcholine biosynthesis cannot be transmitted to offspring via male gametophytes owing to interruption of autophagy-like processes required for pollen germination in Arabidopsis thaliana.

Abstract excerpt

Phosphatidylcholine is a major plant membrane phospholipid that contributes to the biogenesis and desaturation of membrane lipids and storage lipids. Thus, to ensure reproductive capacity, any genetic defect that affects phosphatidylcholine biosynthesis must be eliminated before fertilization. In Arabidopsis thaliana, phosphatidylcholine biosynthesis depends on CCT1 and CCT2, both encoding CTP: phosphorylcholine...

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