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Article

Beyond symptoms: uncovering type 2 inflammation and small airway dysfunction in Treatment-Naïve asthma.

BMC pulmonary medicine - 2 Feb 2026

Nakano Yutaka, Nakano Rika, Yukawa Takuya, Arita Akihiro

Abstract excerpt

BACKGROUND: Despite guideline-based therapy, asthma control remains suboptimal in primary care, suggesting initial assessments may overlook key treatable traits. OBJECTIVE: To assess the prevalence of Type 2 (T2) inflammation and small airway dysfunction (SAD) in treatment-naïve uncontrolled asthma, evaluate the utility of Asthma Control Questionnaire-5 (ACQ-5) in their identification. METHODS: This...

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Identifiers

PMID: 41622158
DOI: 10.1186/s12890-026-04116-2
PMCID: PMC12997940

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