Comprehensive microbiome and metabolome analysis revealed the changes of semen microbial characteristics and metabolic phenotypes in patients with idiopathic oligoasthenozoospermia.

Abstract excerpt

Background: The etiology and pathogenesis of idiopathic oligoasthenospermia (IOA) remain unclear, and current treatment options yield suboptimal outcomes. Consequently, there is an urgent need to identify novel biomarkers and develop diagnostic tools to improve patient identification and clinical management. Multi-omics technologies offer a promising pathway toward achieving this goal in the future. Methods: This...

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