Article
Viruses Previously Classified as CRF146_BC, a Circulating Recombinant Form of HIV-1 Recently Reported in Brazil, Represent Different Recombinant Forms, One of Which Is Circulating in Spain.
Viruses - 12 Jan 2026
Donoso Ana, Moreno-Lorenzo María, Delgado Elena, Cañada-García Javier E, Iribarren José Antonio, Salicio Yolanda, Benito Sonia, Lorente-Sorolla Clara, Del Romero-Guerrero Jorge, Baza-Caraciolo María Begoña, Díez-Fuertes Francisco, Zamarrón Pilar, Téllez Raquel, Miqueleiz Ana, Gómez-González Carmen, Cortizo Sandra, Morano Luis, Thomson Michael M
Abstract excerpt
Circulating recombinant forms (CRFs) are important components of the HIV-1 pandemic. Previous studies have reported the propagation of diverse HIV-1 CRFs of South American origin in Europe. Here, through protease-reverse transcriptase (Pr-RT) and integrase sequence analyses, we identify a Spanish cluster (BC3) branching with a Brazilian virus (10BR_RJ009) previously classified as CRF146_BC. In Pr-RT, BC3...
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