Integrative genome-wide association study and transcriptomic analysis to identify candidate genes and pathways for heterophil and lymphocyte traits in white-feathered broilers.

Abstract excerpt

Enhancing disease resistance is one of the primary objectives of the poultry industry through breeding. The heterophil to lymphocyte ratio (H/L ratio) represents a critical indicator of stress and immune status in chickens. However, the essential genetic networks and functional genes governing the H/L ratio remain uncharacterized. In this study, by combining genomic and transcriptomic data, we aimed to identify...

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