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A 5500-year-old Treponema pallidum genome from Sabana de Bogotá, Colombia

22 Jan 2026

Abstract excerpt

Treponematosis, a bacterial infection caused by Treponema pallidum subspecies and T. carateum (yaws, bejel, syphilis, pinta), has afflicted humans for millennia. Despite paleopathological evidence and emerging genomic data, little is known about the evolutionary history of these pathogens. We report a 5500-year-old Treponema genome (TE1-3) from Middle Holocene hunter-gatherer contexts of the rock shelter...

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PMID: 41570125
DOI: 10.1126/science.adw3020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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