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Article

Weight-loss effects of macronutrient-based diets modified by genetic variants: a protocol for systematic review of randomised controlled trials.

BMJ open - 21 Jan 2026

Subardjo Yovita Puri, Khairunnissa Nabila Monica, Kusuma Rio Jati, Huriyati Emy, Susetyowati Susetyowati

Abstract excerpt

INTRODUCTION: Personalised nutrition that incorporates genetic results into dietary interventions holds significant potential to optimise weight management and metabolic outcomes. While traditional calorie-restricted diets remain effective, emerging evidence suggests that variations in macronutrient distribution may offer additional benefits. Genetic variants help explain interindividual differences in dietary...

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Identifiers

PMID: 41565330
DOI: 10.1136/bmjopen-2025-110935
PMCID: PMC12829392

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