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Trade-off between accumulation potential and transmission efficiency in hypovirus variants infecting phytopathogenic fungi.

mBio - 11 Feb 2026

Yang Shian, Dai Ruoyin, Liu Shujing, Pang Tianxing, Gong Shujuan, Tian Mengyuan, Kang Zhensheng, Chen Hongying, Luo Ming, Andika Ida Bagus, Sun Liying

Abstract excerpt

The high mutation rates of RNA virus replication generate genetically diverse virus variants in infected hosts. However, the effects of mutations on viral fitness and adaptability remain understudied in fungal-virus pathosystems. In this study, a novel hypovirus (single-stranded positive-sense RNA genome, family Hypoviridae), designated Valsa pyri hypovirus 1-α (VpHV1-α), and two of its shorter, less prevalent...

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Identifiers

PMID: 41562596
DOI: 10.1128/mbio.02922-25
PMCID: PMC12892957

Genes

AGO3

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