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Effect of telomere length and related gene polymorphism in signaling pathway on semen quality.

Scientific reports - 16 Jan 2026

Jia Xueshan, Cao Jinhu, Zhang Shengnan, Feng Ke, Li Ju, Guo Haibin, Qu Xiaowei, Tao Ling, Yang Yanyan, Wu Aihua, Ling WeiHang, Zhang Chen, Tian Qingfeng, Zhang Guang-Hui

Abstract excerpt

This study investigates sperm telomere length (STL), gene polymorphisms in telomere-related pathway genes, and semen quality, were detected to evaluate their potential as a biomarkers of semen quality. Associationally, it explores between gene polymorphisms and STL, and semen quality. A total of 1,349 male volunteers from the Pu-yang Reproductive Medicine Center were selected as research subjects. Computer-aided...

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Polymorphism, Genetic
Semen Analysis
Signal Transduction
Sperm Count
Sperm Motility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Telomere Homeostasis

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Open in PubMed Open full text

Identifiers

PMID: 41545405
DOI: 10.1038/s41598-025-34054-8
PMCID: PMC12909296

Genes

POT1
TERT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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