Clinical manifestations of chromosome 19p13.11 duplication.

Abstract excerpt

BACKGROUND: Chromosome 19 is the most gene-dense chromosome in the human genome, with a high frequency of segmental duplications that predispose it to genomic rearrangements. While deletions of chromosome 19 have been associated with various clinical conditions, duplications remain poorly characterised. Here, we report three cases involving 19p13.11 duplication and describe the associated clinical phenotype....

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• Phenotype
• Attention Deficit Disorder with Hyperactivity
• Chromosome Duplication
• Chromosomes, Human, Pair 19
• Craniofacial Abnormalities