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Develop and validate a computable phenotype for identifying alcohol-use disorder patients using structure and unstructured EHR data.

Alcohol and alcoholism (Oxford, Oxfordshire) - 16 Nov 2025

Dai Hao, Tapper Elliot B, Zhao Lili, Scheiffele Grant D, Li Xiaohan, Ramon Ronald, He Xing, Lee Yao An, Guo Jingchuan, Bian Jiang

Abstract excerpt

BACKGROUND: Alcohol Use Disorder (AUD) drives significant morbidity through alcohol-related liver disease. Accurate AUD identification in electronic health records is critical for research and care delivery, yet International Classification of Diseases (ICD) code-based algorithms miss many cases while manual review is impractical at scale. Computable phenotypes (CPs) integrating structured and unstructured EHR...

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PMID: 41501992
DOI: 10.1093/alcalc/agaf086
PMCID: PMC12779471

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