Article
A combined genetic and phenotypic marker approach enables precise detection of hypervirulent Klebsiella pneumoniae and reveals associated traits of capsule overproduction and tellurite resistance.
Microbiology spectrum - 3 Feb 2026
Duong Tran Thi Thuy, Lin Wei-Hung, Tsai Ya-Min, Liao Chun-Hsing, Huang Yun-Tsung, Hsueh Po-Ren, Kao Cheng-Yen
Abstract excerpt
We integrated genetic and phenotypic analyses to characterize carbapenem-resistant hypervirulent K. pneumoniae (CRhvKp) and liver abscess-associated K. pneumoniae (LAKp) isolates, aiming to identify potential biomarkers for the accurate detection of hvKp. A total of 660 carbapenem-resistant K. pneumoniae (CRKp) and 69 LAKp isolates were screened for five hvKp-associated biomarkers (peg-344, iroB, iucA, prmpA,...
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