Article
Predicting PD-L1 expression in advanced EGFR-mutant lung adenocarcinoma patients using NECT, CECT radiomics and clinical features.
BMC cancer - 3 Jan 2026
Li Jinjin, Yang Ziyi, Liu Liangzhong, Tang Fei, Zheng Taihao, Zhang Chao, Peng Yuan, Yang Zhenzhou, Zhou Zhiming, Tan Benxu, Zhang Xiaoyue
Abstract excerpt
OBJECTIVES: Recent studies have applied machine-learning radiomics to predict EGFR mutations or PD-L1 expression, yet little is known about PD-L1 prediction specifically in EGFR-mutant lung adenocarcinoma, despite evidence linking high PD-L1 expression to TKI resistance. To address this gap, this study integrates CT radiomics features with clinical data to develop and validate interpretable models for predicting...
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