Article
Platinum-Based Chemotherapy Versus Secondary Cytoreductive Surgery Before Olaparib Maintenance Therapy for 259 Patients with BRCA Mutated Platinum-Sensitive Recurrent Ovarian Cancer: A Multicenter Retrospective Study: Comparative Effectiveness and Survival Outcomes Analysis.
Annals of surgical oncology - 1 Apr 2026
Yang Dong, Guo Yu, Gao Jialin, Yang Yu, Zhang Yanbin, Zhao Xinxin, Ren Sijia, Wang Chao, Liu Renzi, Bai Wenpei
Abstract excerpt
BACKGROUND: The benefit of secondary cytoreduction surgery (SeCRS) followed by olaparib maintenance therapy for recurrent ovarian cancer has not been clearly demonstrated. This study aimed to evaluate the role of SeCRS combined with olaparib for patients with BRCA-mutated platinum-sensitive recurrent ovarian cancer. METHODS: This multi-center retrospective study analyzed patients with BRCA-mutated...
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