Article
Frequency and Diagnostic Utility of the -13910C>T MCM6 Gene Polymorphism for Lactose Intolerance in a Brazilian Northeast Population.
In vivo (Athens, Greece) - 1 Jan 2026
DE Morais Guilherme Passos, Thé André Pontes, Dias Nogueira Beatriz Maria, DE Sousa Oliveira Deivide, DA Cunha Leidivan Sousa, DA Silva Jean Breno Silveira, Thé Patrícia Maria Pontes, Monteiro Alexandre DE Almeida, Xavier Luis Gonzaga Moura, DE Moraes Maria Elisabete Amaral, Moreira-Nunes Caroline Aquino
Abstract excerpt
BACKGROUND/AIM: Lactose intolerance (LI) is a common clinical condition associated with reduced lactase enzyme activity. The oral lactose tolerance test (OLTT), although widely used for diagnosis, has several limitations such as fasting, multiple blood collections, and gastrointestinal discomfort. As an alternative, genetic testing targeting the -13910C>T polymorphism in the MCM6 gene, a regulator of lactase...
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